March Madness 2025 Sweet 16 Betting Lines, Spreads & Opening Odds
The 2025 NCAA Tournament Sweet 16 matchups are set, with sportsbooks releasing early betting lines for the third round. Here's a comprehensive breakdown of the key games and odds.

Basketball player in red jersey
Arkansas vs Texas Tech (TTU -4.5)
- Texas Tech favored by 4.5 points
- TTU's strength: Averaging 10+ three-pointers per game
- Arkansas's edge: Drawing fouls (20.7 free throw attempts per game)
- Key factor: Arkansas's defense forces 11.8 turnovers per game
Texas Tech advanced by defeating:
- UNC Wilmington (Round 1)
- Drake 77-64 (Round 2)
Arkansas's path included upsets over:
- #7 Kansas (Round 1)
- #2 St. John's 75-66 (Round 2)
Michigan vs Auburn (Auburn -7.5)
- Auburn opened as 7.5-point favorites
- Michigan's key win: Comeback victory over Texas A&M
- Roddy Gayle Jr.: 26 points in second round
- Auburn's strength: 36.6% three-point shooting
- Critical matchup: Michigan's defense vs Johni Broome
Key Statistics:
- Michigan's advantage: Interior defense
- Auburn ranks 5th nationally in turnover rate
- Michigan's frontcourt: Vladislav Goldin and Danny Wolf combined for 37 points, 21 rebounds in Round 2
For live odds updates and complete tournament coverage, check with major sportsbooks like DraftKings, BetMGM, and Caesars.
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