The No. 3 Ohio State Buckeyes take on Michigan State in their 50th all-time matchup this Saturday. The odds heavily favor Ohio State, who sits second in the Big 10 East, while Michigan State occupies last place with a 3-3 record.

Key Betting Lines:

• Spread: Ohio State -25.5
• Over/Under: 63 points
• Moneyline: Ohio State -10000, Michigan State +1600

Key Stats:

• Ohio State leads FBS in total points scored
• Michigan State averages 27 points per game but only 13 against top opponents
• Combined average points against both teams: 37.4
• Ohio State is 3-2 on over/under bets
• Michigan State is 1-4 on over/under bets
• Ohio State covers the spread 50% of the time as favorite
• Michigan State is 2-0 as favorite, 0-3 as underdog

Analysis: The large spread reflects Ohio State's dominance, coming off two 40+ point wins. While Michigan State has struggled this season, the over/under of 63 points seems high given both teams' strong defenses. Ohio State's inconsistency in covering spreads and Michigan State's poor over/under record suggest betting the under may be the smart play.

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