A highly anticipated Top 25 showdown takes place Saturday night as No. 5 Ohio State (6-1) hosts No. 20 Penn State (5-2) at Ohio Stadium. Kickoff is set for 7:30 p.m. EST on ABC.

The Buckeyes enter on a five-game win streak, most recently dominating Indiana 54-7. Penn State looks to bounce back after a tough 20-18 nine-overtime loss to Illinois.

Betting Odds:

• Ohio State -18.5 (-110)
• Penn State +18.5 (-110)
• Over/Under: 59.5 (O: -115, U: -105)

Keys for Ohio State:

• Continue offensive momentum behind QB CJ Stroud (266 yards, 4 TDs vs Indiana)
• Maintain defensive pressure (5 sacks last week)
• Feature RB TreVeyon Henderson in ground game
• Build on four straight wins by 39+ points

Keys for Penn State:

• Get QB Sean Clifford back to form after injury
• Establish Clifford-Dotson passing connection
• Leverage #6 ranked defense in yards per play
• Contain Ohio State's explosive offense

Prediction: While Ohio State's offense presents major challenges, Penn State's strong defense should keep this closer than the 18.5-point spread suggests. Expect a competitive prime time battle between these Big Ten rivals.

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