Penn State comes to Columbus seeking redemption after their playoff hopes were dashed in a nine-overtime loss to Illinois. The Buckeyes, leading the Big Ten East at 4-0, look to continue their dominant run against their emerging rival.

Ohio State's offense has been explosive, leading college football with 49.3 points per game. After early season struggles, they've won their last five games by margins of 21-52 points. Their defense ranks 17th nationally, allowing 18.6 points per game.

Penn State (2-2 in conference) has shown resilience despite injuries, including to QB Sean Clifford. Their losses have been close - just five points combined - while their wins have been convincing, including a ranked victory over Auburn.

Key Matchup Analysis:

• Ohio State's high-powered offense vs Penn State's #3 ranked defense (14.3 ppg)
• Penn State's 81st ranked offense (25 ppg) vs improving Ohio State defense
• Critical factor: Penn State's top-ranked pass defense (4.9 yards/attempt) against OSU's big-play ability

The Spread: Ohio State -18.5

• Ohio State has proven they can cover large spreads
• Success depends on establishing the run game to wear down Penn State's defense
• A close game is possible if Penn State's defense contains Ohio State's explosive plays

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