Ohio State Buckeyes 2022 Betting Guide: Top Preseason Wagers and Predictions

Ohio State Buckeyes 2022 Betting Guide: Top Preseason Wagers and Predictions

By Michael Davidson

February 25, 2025 at 09:48 AM

After missing the College Football Playoff in 2021 with an 11-2 record (8-1 Big Ten), the Ohio State Buckeyes are poised for a strong 2022 campaign. Here are the top betting opportunities for the upcoming season:

Ohio State vs Notre Dame (-14.5) - Week 1

  • Home game advantage in Columbus
  • College GameDay atmosphere
  • Superior talent and experience favors Buckeyes covering spread
  • Strong value at -110 odds

National Championship Odds (+250)

  • Third-best odds behind Alabama and Georgia
  • Return of sophomore QB CJ Stroud
  • Improved defensive coaching staff
  • 6 of 9 bowl-eligible opponents at home
  • Michigan rivalry game at home

CJ Stroud Heisman Trophy (+175)

  • Current Heisman favorite
  • 2021 stats: 4,435 yards, 44 TDs, 72% completion
  • Ranked 5th in yards, 3rd in TDs, 1st in QBR
  • Returns top targets including Jaxson Smith-Njigba
  • Additional weapons in Marvin Harrison Jr. and Julian Fleming

The Buckeyes have the talent, schedule, and motivation to contend for both team and individual honors in 2022. Their loss to Michigan last season (42-27) ended playoff hopes, but the Rose Bowl win over Utah (48-45) showed their resilience. With an experienced quarterback and improved defense, Ohio State offers strong betting value across multiple markets.

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