Here's the concise betting guide for MLB Opening Day (April 12, 2022):

Boston Red Sox at Detroit Tigers (1:11 pm ET)

• Spread: Boston -1.5
• Total: 9 runs
• Best Bets: Boston -1.5, Over 9 runs
• Key Factor: Red Sox looking to bounce back after slow start

Seattle Mariners at Chicago White Sox (4:11 pm ET)

• Spread: Chicago -1.5
• Total: 9 runs
• Best Bets: Chicago -1.5, Over 9 runs
• Key Factor: White Sox offense ranking 3rd in MLB (6.33 runs/game)

Cleveland Guardians at Cincinnati Reds (4:11 pm ET)

• Spread: Cleveland -1.5
• Total: 8 runs
• Best Bets: Reds +1.5, Under 8 runs
• Key Factor: Elite pitching matchup between Bieber and Mahle

Toronto Blue Jays at New York Yankees (7:06 pm ET)

• Spread: New York -1.5
• Total: 9.5 runs
• Best Bets: Blue Jays +1.5, Over 9.5 runs
• Key Factor: Toronto's hot offense (tied for 2nd in MLB HRs)

Houston Astros at Arizona Diamondbacks (9:40 pm ET)

• Spread: Houston -1.5
• Total: 9.5 runs
• Best Bets: Houston -1.5, Under 9.5 runs
• Key Factor: Diamondbacks struggling offense (2.75 runs/game)

San Diego Padres at San Francisco Giants (9:46 pm ET)

• Spread: San Diego -1.5
• Total: 7.5 runs
• Best Bets: Giants +1.5, Over 7.5 runs
• Key Factor: Strong historical matchups for both teams' hitters

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