Guardians vs. White Sox September 21: Division Lead on the Line in Critical AL Central Showdown

Guardians vs. White Sox September 21: Division Lead on the Line in Critical AL Central Showdown

By Michael Davidson

March 1, 2025 at 10:17 PM

The Cleveland Guardians (81-67) face the Chicago White Sox (76-72) at Guaranteed Rate Field on September 21 at 8:10 p.m., following their thrilling 10-7 extra-innings victory on Tuesday.

Game Details:

  • White Sox are favored (-127)
  • Guardians moneyline: +112
  • Run line: Cleveland +1.5 (-193)
  • Over/Under: 7.5 runs

Pitching Matchup:

  • Guardians: Triston McKenzie (10-11, 3.08 ERA, 0.97 WHIP)
  • White Sox: Lance Lynn (7-5, 3.99 ERA, 1.07 WHIP)

Key Stats:

  • McKenzie: 167 K's in 172.1 innings, allowed 5 ER in last 19.2 innings
  • Lynn: Won last 4 starts, 3 ER in last 26.1 innings
  • Jose Ramirez vs Lynn: .345, 4 HR, 8 RBI in 29 AB
  • Seby Zavala vs McKenzie: 2 HR, 5 RBI in 6 AB

Stakes:

  • Guardians lead AL Central by 5 games with 14 remaining
  • Must-win game for White Sox's playoff hopes
  • Cleveland can secure series win and extend division lead to 6 games

The Guardians aim to capitalize on their momentum after Tuesday's win, while the White Sox face a do-or-die situation to keep their playoff hopes alive. With both starting pitchers performing well recently, this matchup could come down to late-game execution.

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