No. 16 Colorado (8-2) visits Kansas (4-6) in a crucial Big 12 matchup on Saturday at 3:30 p.m. ET on FOX. This marks their first meeting since 2010, with both teams riding impressive betting streaks - Colorado has covered eight straight while Kansas has won four consecutive against the spread.

Game conditions at Memorial Stadium look favorable, with sunny skies and temperatures in the upper 50s expected at kickoff.

Colorado enters as a 2.5-3 point road favorite, with the total set at 59.5 across major sportsbooks. The Buffaloes' moneyline sits at -142 (DraftKings), while Kansas can be found at +125 (BetMGM).

Key Matchups:

• Colorado's passing attack vs Kansas secondary
• Travis Hunter (911 receiving yards) vs Cobee Bryant (4 INTs)
• Kansas RB Devin Neal (926 yards, 12 TDs) vs Colorado's improving run defense

Colorado's offense relies heavily on QB Shedeur Sanders and two-way star Travis Hunter, ranking last in rushing but excelling in explosive plays. Kansas counters with dual-threat QB Jalon Daniels and a strong ground game led by Neal.

The Jayhawks have won consecutive games against ranked opponents for the first time in school history, while Colorado sits atop the Big 12 standings with playoff aspirations.

Prediction:

• Colorado -2.5
• Over 59.5

Reasoning: Colorado's big-play ability and momentum should overcome Kansas's home-field advantage in what projects to be a high-scoring affair. Both teams are playing their best football, but the Buffaloes' superior talent should prevail in a close contest.

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