The Tampa Bay Buccaneers (4-1) head to Philadelphia as 6.5-point favorites for Thursday Night Football against the Eagles (2-3). Here's what you need to know:

Tampa Bay Buccaneers Overview:

• Coming off a dominant 45-point performance vs Dolphins
• Tom Brady threw 5 TD passes last week
• Road struggles: 1-1 record, under 25 points per game
• Brady dealing with thumb injury
• Strong home offense (30+ points) but weaker on road

Philadelphia Eagles Overview:

• Broke 3-game losing streak last week vs Panthers
• Rallied from 15-3 deficit to win
• Jalen Hurts struggled (<200 passing yards, 0 TDs)
• Currently 2-3, looking to reach .500
• Run game needs improvement (Sanders <50 yards last week)

Key Factors:

• Brady's thumb injury could impact Bucs' offensive production
• Eagles must establish running game early
• Bucs historically struggle in Thursday night road games
• Eagles defense needs to contain Brady's passing attack
• Philadelphia needs more offensive production from Hurts

The game's outcome likely hinges on Brady's thumb injury and the Eagles' ability to establish their run game. While Tampa Bay boasts the stronger offense, their road performance and Brady's injury create uncertainty. The Eagles will need a complete offensive effort to upset the favored Buccaneers.

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