The No. 5 ranked Ohio State Buckeyes face the Indiana Hoosiers in a Saturday night ESPN matchup at 7:30 pm EST in Bloomington. Ohio State enters as 19-point favorites after winning four straight games by 21+ points since their early loss to Oregon.

Game Details:

• Spread: Ohio State -19 (-110)
• Over/Under: 60 points (-110)
• Series Record: Ohio State leads 76-12-5

Ohio State Overview:

• Currently ranked #5 in AP Poll
• Lead NCAA in points/game, yards/game, and yards/play
• Won last 4 games by 21+ points
• Coming off bye week
• CJ Stroud leading consistent offensive attack

Indiana Overview:

• 2-4 record after starting season ranked
• Struggling offense ranks 122nd in points/game
• QB Michael Penix: 4 TDs, 7 INTs this season
• Close 20-15 loss to Michigan State last week
• Defense will need major adjustments

Prediction: The Buckeyes' high-powered offense and improving defense should be too much for a struggling Indiana team. Expect Ohio State to control the game and win convincingly on the road as they push for a College Football Playoff spot.

Key factors:

• Ohio State's offensive firepower
• Indiana's offensive struggles
• Buckeyes' momentum and playoff hopes
• Series history favors Ohio State heavily

The Buckeyes should cover the spread and continue their dominant run through Big Ten play.

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