The Indianapolis Colts face the Arizona Cardinals on Christmas night in a crucial Week 16 matchup between playoff contenders. The Cardinals enter as slight 1-point home favorites despite recent struggles.

The Colts come in hot, winning 5 of their last 6 games, including a 27-17 victory over New England last week. Jonathan Taylor continues to power their offense with over 1,500 rushing yards, while Carson Wentz has limited turnovers with just 6 interceptions this season.

The Cardinals are looking to bounce back after a shocking loss to Detroit where they scored only 12 points as 12-point favorites. Their defense has allowed 30+ points in consecutive games, raising concerns as they face the Colts' potent rushing attack.

Key Factors:

• Colts' rushing attack led by Jonathan Taylor will be crucial for controlling time of possession
• Cardinals' defense needs to improve after allowing 30+ points in back-to-back games
• Arizona's offense must rebound from poor showing against Detroit
• Colts aim to extend their winning streak while Cardinals try to avoid third straight loss

The outcome likely hinges on whether Arizona's defense can contain Taylor and the Colts' ground game while their offense returns to early-season form. The Colts' ball-control strategy could be the difference-maker in this holiday matchup.

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