The Cleveland Guardians (48-46) face the Boston Red Sox (48-48) in a four-game series opener at Fenway Park, with first pitch at 7:10 pm ET.

Game Preview:

• Boston is favored at -112 (Guardians at -104)
• Run line: Boston +1.5 (-188)
• Over/under: 9.5 runs

Pitching Matchup:

• Guardians: Zach Plesac (2-7, 4.02 ERA, 68 K in 94 IP)
• Red Sox: Nick Pivetta (8-7, 4.50 ERA, 104 K in 108 IP)

Key Storylines:

• Guardians split recent series with White Sox, seeking improvement on 23-27 road record
• Red Sox struggling badly, having lost 9 of last 10 and coming off sweep by Blue Jays
• Boston outscored 40-10 in weekend series vs Toronto

Players to Watch:

• Jose Ramirez (CLE): .287/.362/.570, 19 HR, 78 RBI, 54 runs, 13 SB
• Rafael Devers (BOS): Hitting .331/.400/.615 with 10 HR at Fenway
• Andres Gimenez (CLE): 2-for-3 with HR vs Pivetta historically
• Austin Hedges (CLE): 2-for-9 with 2 HR vs Pivetta

Analysis: Cleveland has momentum advantage facing slumping Boston team that's allowed 67 runs in last five games. While Plesac has struggled to get wins, he matches up well against struggling Red Sox pitching. The Guardians' offense should have opportunities against Pivetta, who's allowed 20 runs in his last 13.1 innings.

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