The San Francisco Giants (25-16) face the Cincinnati Reds (19-20) in the second game of their four-game series at Great American Ballpark. First pitch is scheduled for 6:40 pm ET.

The Giants won Monday's opener 6-3, powered by three home runs and six scoreless innings from Logan Webb. Tyler Naquin and Eugenio Suarez homered for the Reds in the loss.

Game Details:

• Reds are favored at -126
• Giants moneyline: +108
• Run line: San Francisco +1.5
• Over/under: 8 runs

Pitching Matchup:

• Giants: Anthony DeSclafani (3-1, 2.14 ERA)
• Reds: Luis Castillo (1-5, 7.71 ERA)

Key Stats:

• Reds lead MLB in runs/game (5.39)
• Giants rank 15th (4.33 runs/game)
• Giants rank 2nd in runs allowed (3.50/game)
• Reds rank 28th in runs allowed (5.34/game)

Notable Performers:

• Giants: Brandon Crawford leads team with 9 HR, 22 RBI
• Reds: Nick Castellanos batting .331/.391/.627 with 10 HR, 25 RBI
• Eugenio Suarez heating up: .276/.313/.552 with 2 HR last week

The matchup features DeSclafani's return to Cincinnati to face his former team, while Castillo looks to turn around his struggling season. The Giants aim to maintain MLB's best record while the Reds seek to climb back to .500.

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